Phenylketonuria or PKU is an inherited metabolic disorder in which the individual with the disorder is unable to produce a specific enzyme for digestion of the Amino Acid Phenylalanine. This causes a build up in the body which can result in severe mental retardation.

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Ryan's PKU Foundation of Virginia is dedicated to providing a support network to individuals with PKU and their families; Promoting PKU wellness through increasing public awareness, developing and distributing educational materials, supporting research and sharing information among families.